Eligibility of Plasma Donor
In addition to the donor
eligibility criteria for whole blood
donation, the following criteria should be met for potential plasma
donors –
-
Donors who have had transfusion of blood products in last 8 weeks
will be excluded
-
Donors who have had COVID diagnosis more than 4 months will be
excluded from donation
-
Males or nulliparous female donors of weight >55Kg. To avoid the
risk of Transfusion Related Acute Lung Injury (TRALI) preference
should be given to use of plasma from male donors or from female
donors who have never been pregnant including abortions.
-
Prior diagnosis of COVID-19 documented by an approved laboratory
test (preferably RT-PCR) with symptomatic disease with at least
fever and cough
-
Complete resolution of symptoms at least 28 days prior to donation
or Complete resolution of symptoms at least 14 days prior to
donation and negative real time PCR test for COVID-19 from
nasopharyngeal swab.
Screening of Donors before the donation
-
Physical examination of the donor to establish good health
including absence of fever and respiratory. Donors not fit to
donate blood based on the history and examination will be deferred
and excluded from plasma donor pool.
-
Two blood samples (small volume – 5ml) will be drawn for the
following pre-donation tests
-
Blood group (ABO grouping and Rh phenotyping) and antibody
screening for clinically significant antibodies (Extended Rh,
Kell, Duffy, Kidd, MNS)
-
Complete blood count (CBC). Donors with Hb>12.5g/dl, platelet
count >1,50,000 per microliter of blood and TLC within normal
limits will be accepted.
-
Screening for syphills, malaria, HIV, HBV and HCV by serology
or NAT.
-
Total serum protein. Donors with total serum protein > 6gm/dl
will be accepted
-
Presence of IgG and IgM antibodies to COVID-19 by rapid test.
Neutralizing titer of donor plasma should be above the
specific threshold (if the latter is not available, plasma IgG
titer (against S-protein RBD) above 1:640 should be used).
See the generic blood donation criteria here
*These are some of the most common criteria and is not a complete list of
exclusions/eligibility criteria. These criteria may change or vary across blood banks and hospitals. In case of
any doubt, please ask a medical expert.